Jackie tests the drug on a depressed young woman (Misty Mundae) who immediately becomes a maniacal love machine that ravishes Jackie in her office. Turned on by the encounter, Jackie decides to experience the effects of the drug firsthand, and it transforms her from a plain and mousy doctor into a stunning and sensuous vixen who craves endless erotic satisfaction. Stalking the streets at night as her predatory alter ego, Jackie indulges all her deepest lesbian fantasies. A smouldering one-night-stand with a hooker leads to further steamy seductions, menacing menages-a-trois, and a wild encounter with Jackie's own house maid (Ruby LaRocca) who fails to even recognize her. As Jackie becomes more and more addicted to the drug and the carnal pleasures it promises, she begins to lose all control…and who knows how far she will go to satisfy her 'other' insatiable self.